https://tulparus.ai/research/ Short notes on unresolved genetic cases: how we think about the problems, how we evaluate the models, and what we will not claim. en Wed, 14 Oct 2026 09:00:00 GMT https://tulparus.ai/research/unknown-is-not-absent/ https://tulparus.ai/research/unknown-is-not-absent/ Wed, 14 Oct 2026 09:00:00 GMT A referral letter tells us what a patient has. It rarely tells us everything that was examined, ruled out, or never investigated. https://tulparus.ai/research/beyond-known-disease-genes/ https://tulparus.ai/research/beyond-known-disease-genes/ Mon, 05 Oct 2026 09:00:00 GMT Sequencing comes back and the case stays open. Sometimes the answer is in a gene whose link to disease is not yet established, or only weakly so. https://tulparus.ai/research/a-rank-is-not-a-probability/ https://tulparus.ai/research/a-rank-is-not-a-probability/ Sat, 26 Sep 2026 09:00:00 GMT A ranking tells you where to look first. It does not tell you how likely you are to find the answer. https://tulparus.ai/research/knowledge-releases-and-the-second-look/ https://tulparus.ai/research/knowledge-releases-and-the-second-look/ Fri, 18 Sep 2026 09:00:00 GMT A patient has exome or genome sequencing. The findings are reviewed, the report is issued, and the case stays unresolved. https://tulparus.ai/research/why-a-person-signs-off/ https://tulparus.ai/research/why-a-person-signs-off/ Wed, 09 Sep 2026 09:00:00 GMT AI can investigate, weigh evidence and propose conclusions. Clinical responsibility stays human. https://tulparus.ai/research/when-evidence-conflicts-context-matters/ https://tulparus.ai/research/when-evidence-conflicts-context-matters/ Sun, 30 Aug 2026 09:00:00 GMT Scientific evidence does not always agree. A reliable investigation makes the differences visible instead of hiding them.